# Chronic Fatigue Syndrome - Author: **Johns Hopkins Medicine** - Document Tags: [[chronic fatigue syndrome]], [[Chronic Fatigue Syndrome]] - [URL link](https://www.hopkinsmedicine.org/health/conditions-and-diseases/chronic-fatigue-syndrome)  ## Highlights - Chronic fatigue syndrome (CFS) is characterized by profound tiredness, regardless of bed rest. Its symptoms may worsen with physical or mental activity. CFS can happen suddenly and last for years. ([View Highlight](https://read.readwise.io/read/01hj9dhnkv1hyrtb2m55jve0zb)) --- - The cause of CFS is not known. ([View Highlight](https://read.readwise.io/read/01hj9dh3pmjz530rfmchmdxjjw)) --- - Symptoms of CFS often mimic the flu. ([View Highlight](https://read.readwise.io/read/01hj9dj75y70g1fm7k1fzqfmyb)) --- - • Sensitivity to light • Headache • Tender lymph nodes • Fatigue and weakness • Muscle and joint pain • Inability to concentrate • Insomnia • Forgetfulness • Mood swings • Confusion • Low-grade fever • Depression ([View Highlight](https://read.readwise.io/read/01hj9djcpmfyy8d389hv9qzvcw)) --- - Four or more symptoms of CFS are present. ([View Highlight](https://read.readwise.io/read/01hj9djqy1kpt6x6z8eqmzycej)) --- - A specific treatment for CFS has yet to be proven effective. Vitamin supplements and medicines have some benefit. Many treatments just relieve the symptoms of CFS. ([View Highlight](https://read.readwise.io/read/01hj9dk3jxwhav1kpd0ctnpt2v)) --- - CFS happens up to 4 times more often in women than in men ([View Highlight](https://read.readwise.io/read/01hdhqytexz7kcqt5gtgex4yff)) --- - Treatment may include: ([View Highlight](https://read.readwise.io/read/01hdhr167acr2my3bcmmrq6n5y)) --- - Light-intensity aerobic exercise (but avoid moderate to vigorously intense physical activity) ([View Highlight](https://read.readwise.io/read/01hdhr14bhhwdsn7s5f1sxreat)) ---